Catalog Number - 58022-N13-K

The 58022-N13-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput membrane filters engineered for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring maximum sample purity and reproducible analytical results in high-volume workflows.

The 13 mm format is optimized for low sample volume applications, enabling efficient filtration with minimal sample loss, making it ideal for analytical labs, method development, and high-value sample workflows.

✅ Critical Compliance Advantage (No Flush Required)

These filters are validated and certified to meet stringent regulatory requirements, including:

• US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release

• USP <788> for particulate matter in injectables

• USP requirements for “Sterile Water for Injection”

Because of this validated performance:

• ✅ No initial flushing is required

• ✅ No need to discard the first 200 µL of filtrate

• ✅ Preserves valuable samples—critical for small-volume workflows

• ✅ Saves time and reduces risk of failed methods and costly investigations

👉 This provides a major operational and compliance advantage for QC/QA laboratories, especially in regulated and high-throughput environments where reproducibility, efficiency, and audit readiness are essential.

Performance & Design

The 0.22 µm pore size is designed for sterile filtration and fine particulate removal, ensuring maximum clarity and protection of analytical instrumentation.

Nylon‑66 membrane chemistry ensures broad compatibility with aqueous and organic HPLC solvents, while maintaining ultra-low adsorption—even for charged analytes, supporting accurate quantitation.

The 13 mm design minimizes hold-up volume, maximizing recovery from limited or high-value samples, making it ideal for precision analytical workflows.

The purple color coding allows immediate identification of 0.22 µm nylon filters, and each case includes a Certificate of Analysis to support full compliance and traceability.

Key Features

0.22 µm Nylon‑66 Membrane (Pharma Grade)

• Ideal for sterile filtration and fine particulate removal

• Ensures maximum sample clarity and system protection

✅ No Initial Flush Required (Validated)

• Extractable-free from first filtrate

• Eliminates sample waste and variability

Ultra-Low Adsorption

• Suitable for charged and sensitive analytes

• Maximizes analyte recovery

Optimized for Low Sample Volumes (13 mm)

• Minimizes sample loss

• Ideal for analytical and method development workflows

Regulatory Compliance

• Meets FDA CFR Title 21 requirements

• Complies with USP <788>

• Suitable for Sterile Water for Injection

Broad Solvent Compatibility

• Compatible with aqueous and organic solvents

• Ideal for mixed HPLC mobile phases

Autoclavable & EO Sterilizable

• 121°C for 30 minutes or Ethylene Oxide

Color-Coded (Purple)

• Identifies 0.22 µm nylon filters

Bulk Packaging (1000/Case)

• Reduces cost per analysis

• Ideal for high-throughput QC environments

Typical Applications

• HPLC & UHPLC Sample Preparation – fine particulate removal prior to injection

• Sterile Filtration – bacterial and contaminant removal

• Dissolution Testing – pharmaceutical QC workflows

• Regulated Laboratory Methods – validated and compliant processes

• Pharmaceutical Analysis – injectables and formulations

• High-Throughput QC Labs – consistent and efficient performance

Specifications

• Filter Type: Syringe Filter (Pharma Grade)

• Membrane Material: Nylon‑66

• Pore Size: 0.22 µm

• Diameter: 13 mm

• Housing Material: Polypropylene (PP)

• Color Code: Purple (0.22 µm Nylon)

• Connection Type: Luer Lock / Slip

• Chemical Compatibility: Aqueous and organic solvents

• Extractables: None detectable (no flush required)

• Sterilization: Autoclave or EO

• Compliance: FDA CFR 21, USP <788>

• Certification: Certificate of Analysis included

• Sterility: Non-sterile

• Pack Size: 1000/Case

• Brand: AQ™

Resources & Ordering Options

• Order Nylon‑66 syringe filters, 0.22 µm, 13 mm – 100/pack quantity

• Purchase Nylon‑66 syringe filters, 0.22 µm, 13 mm – 50/pack quantity